PACAP38 induces migraine-like attacks in patients with migraine without aura
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منابع مشابه
BRAIN A JOURNAL OF NEUROLOGY PACAP38 induces migraine-like attacks in patients with migraine without aura
Experimental studies have shown that infusion of vasoactive neurotransmitters may trigger headache or migraine-like attacks in man. Pituitary adenylate cyclase activating peptide-38 (PACAP38) is a strong vasodilator found in trigeminal sensory and parasympathetic perivascular nerve fibers. We therefore hypothesized that infusion of PACAP38 would cause headache in healthy subjects and migraine-l...
متن کاملPACAP38 induces migraine-like attacks in patients with migraine without aura.
Experimental studies have shown that infusion of vasoactive neurotransmitters may trigger headache or migraine-like attacks in man. Pituitary adenylate cyclase activating peptide-38 (PACAP38) is a strong vasodilator found in trigeminal sensory and parasympathetic perivascular nerve fibers. We therefore hypothesized that infusion of PACAP38 would cause headache in healthy subjects and migraine-l...
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This study examined the efficacy of lamotrigine in the prevention of migraine aura. Fifty nine patients suffering from migraine with aura received lamotrigine in a controlled three year prospective open study. Treatment response was defined as a reduction of aura frequency each month by at least 50%. Primary endpoint was reached by three quarters of the patients. Lamotrigine significantly reduc...
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ژورنال
عنوان ژورنال: Brain
سال: 2008
ISSN: 1460-2156,0006-8950
DOI: 10.1093/brain/awn307